The church of San Francesco a Ripa was built in 1231 on the site of the chapel and hospice of San Biagio, where St Francis had stayed in 1219. The present appearance of the church is the result of work done in the 17th and 18th centuries.
The Cappella Altieri, in the left transept, is home to the famous funerary monument to the Blessed Ludovica Albertoni, a late work by Gian Lorenzo Bernini (1598-1680).
The wooden statue of St Francis with Two Angels (pre-1588), on the ornate high altar (1746), has been attributed to Fra' Diego da Careri. The painter Giorgio di Chirico (1888-1978), founder of the Metaphysical School, is buried in a small room beyond the first chapel on the left.