The Chapel of St Helen, in the church of Santa Croce in Gerusalemme, lies at the original level of the ancient Sessorium, once the residence of Helen, mother of the emperor Constantine (r. 306-37).
The original 5th century mosaics were replaced; their design has been attributed to Melozzo da Forli (1438-94). The mosaics depict Christ and the four Evangelists, St Peter and St Paul, St Helen and Cardinal Caravajal, and Pope St Silvester I.
The frescoes below the mosaics depict the finding of the True Cross and were painted in 1590 by Niccolò Circignani (c. 1530 - c.1598), better known as il Pomarancio.
The statue of St Helen has been adapted from an ancient statue of the goddess Juno, which was unearthed at Ostia Antica.